Arc-1 review

Take a low dose here and you pay less for it. Arc-1 publishes a price against every milligram rung on both molecules, and the bottom rung is the cheapest thing it sells — that is the structure this site is looking for, and very little of this category runs it. You can also see, before paying, exactly what titrating up will cost you. Two things will cost you if you misread them. The rate in the site-wide banner is not a monthly rate: no monthly plan is sold at it. It exists only as the lowest tirzepatide three-month plan, and that plan's own text says it cannot be canceled partway, so a three-payment commitment is being quoted to you as a monthly figure. And the checkout comes before the intake here — the card is charged first, the prescriber review happens after. It names no compounding pharmacy, and it will not ship to five places.

Vs median

$30/mo above the $169 median across the 242 of 373 programs we track that publish a plain monthly rate

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Quotes off the lowest dose

Consult

Included in the price

Dietitian

Not included

Labs

Not required

Pricing

Varies by dose, plan or tier

Price last updated

August 2026

Arc-1 does not publicly identify the pharmacy that fills its prescriptions. No bloodwork is required before you start. A clinician review is included in the price.

Arc-1 sells compounded semaglutide and compounded tirzepatide as once-weekly self-injections through a storefront that prices each dose band separately, and it says so on the product page itself: "Semaglutide prices vary depending on dosage and treatment duration." Six rungs across the two molecules are published and purchasable, so the cost of every step is visible before anything is bought. Payment comes before the medical intake — the buy button reads "Complete Checkout ($0 consultation fee)", and the intake form and prescriber review follow the charge. No compounding pharmacy is named, and five places are excluded from shipping.

The site-wide banner advertises "GLP-1s starting at $149.99/month", but no month-to-month GLP-1 is sold at that price. It exists only as the tirzepatide 2.5 mg three-month plan, whose own text says it "Cannot be canceled mid-plan" — a three-payment commitment quoted as a monthly rate

• You check out before the intake. The buy button reads "Complete Checkout ($0 consultation fee)" and both the intake form and the prescriber review come after the money moves
• The semaglutide 2.5 mg quarterly plan is a single $250-off charge for a 90-day supply that "Auto-renews at listed price every 3 months" — a large recurring charge rather than a monthly one
• The "LegitScript Certified" claim rests on a self-hosted seal image linking to a keyword search rather than to a seal record, and no seal identifier is published
• No compounding pharmacy is named — only "accredited compounding pharmacies" and "US-Licensed Pharmacies"
• Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven

Arc-1 is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• What microdosing GLP-1 costs
• Low dose vs full dose
• What a flat price costs at a low dose
• The true annual cost of a plan