Sipra review

Sipra is one of the few sellers where choosing a microdose actually lowers the bill. Both compounded semaglutide and tirzepatide come as a microdose injection, a standard injection and a dissolving tablet, and on every plan length the microdose is the cheapest of the three. It is also unusually honest about what a microdose is: its own page says there is no clinical definition of one and that it has not been studied in its own trials. The catch is commitment. There is no month-to-month plan on the pricing page; the shortest is three months paid up front, and three-month plans cannot be refunded once a physician approves you, whether or not anything has shipped. The headline from-price is the twelve-month rate. Its terms describe a one-month plan the pricing page does not offer. Nothing is charged before approval, the pharmacies are named, messaging is available at any hour, and labs are extra. The company's address is a Wyoming registered agent.

Vs median

Not comparable — published against a multi-month block with no monthly rung, so a per-month figure would be one we calculated rather than one they published

Market

$59–$1,300/mo is the full published spread on this site

Structure

Charges less for less

Consult

Included in the price

Dietitian

Not confirmed

Labs

Optional

Pricing

Flat at every dose

Sipra names its pharmacy: Valiant Compounding · Perfect RX · Epiq Scripts. Bloodwork is offered but not required. A clinician review is included in the price.

Sipra LLC calls itself a technology and marketing platform; care comes from an OpenLoop-affiliated medical group, and prescriptions go to named pharmacies including Valiant Compounding Pharmacy and Perfect RX. It sells compounded semaglutide and tirzepatide as weekly injections, as dissolving tablets, and as a separate microdose injection for each drug, which it prices below the standard injection on every plan length. Its microdose page says plainly that there is no clinical definition of a microdose and that it has not been studied in its own trials. The price depends on plan length, not dose. Plans run three, six or twelve months, paid up front, though its terms also mention a one-month plan that the pricing page does not show. Care includes messaging at any hour and physician follow-ups. It ships to all 50 states, with availability varying by state. The company's address is a Wyoming registered agent.

No month-to-month option is published: the shortest plan is three months paid up front

• Three-month plans are not refundable once approved, whether or not anything has shipped
• The headline from-price is the twelve-month rate
• The terms mention a one-month plan that the pricing page does not offer
• Labs are billed separately, and the company's only address is a Wyoming registered agent
• Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven

Sipra is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• What microdosing GLP-1 costs
• Sublingual troches and drops
• The true annual cost of a plan
• Microdose & reconstitution calculator