RxPepsDirect review

This is the most transparent dose disclosure here. RxPepsDirect publishes the vial size, the concentration, the units per injection and the resulting weekly milligram figure for both molecules, in the product's own the search listing: the entry semaglutide vial is 1.2 mg at 0.6 mg/mL, dosed as twenty units once weekly for 0.12 mg a week within a stated range of 0.1 to 0.25 mg. That matters because most products sold as a microdose never say what dose they are, and several turn out not to be low at all. It names Optimal Balance Pharmacy, states 503A compounding, and describes its own model plainly — the drug is sold near cost and the margin sits in a flat medical visit fee. Read that fee carefully, because it is the whole catch: it recurs on refills rather than onboarding you once, and once shipping is added a first semaglutide order costs roughly three times the vial price. The site also contradicts itself on whether twenty-five units is a weekly or twice-weekly dose, which leaves the supply period the entry vial actually covers unsettled. Coverage is 28 states.

Vs median

Not comparable — no per-month rate is published — the verified string carries no monthly figure

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Charges less for less

Consult

Billed separately

Dietitian

Not included

Labs

Not required

Pricing

Varies by dose, plan or tier

Price last updated

August 2026

RxPepsDirect dispenses through a 503A facility. No bloodwork is required before you start. A clinician review is billed separately.

RxPepsDirect is a telehealth prescriber that sells 503A-compounded peptides at what it describes as pharmacy wholesale pricing, with its margin taken in a flat medical visit fee rather than in the drug. It names Optimal Balance Pharmacy as the dispensing pharmacy and states the arrangement plainly: "pay what Optimal Balance Pharmacy actually charges". Both GLP-1 microdose products are sold by the vial with the milligram content, the concentration and the intended units-per-injection published in the product's own the search listing — a level of dose disclosure almost nothing else here matches. It is licensed in 28 states.

The $25 headline is the drug only — the flat $39 medical visit fee and $15 shipping bring a first order to $79, and the visit fee recurs on refills rather than being a one-time onboarding charge

• A 1.2 mg vial at 0.12 mg/week is a ten-week supply on paper, but the site's own pages disagree on whether 25 units is a once- or twice-weekly dose, so the supply period a $25 vial actually covers is ambiguous
• Licensed in 28 states, so roughly two in five readers cannot buy at any price
• Rungs above the starting vial are marked "Active Rx Required", so the advertised entry price is not the price of continuing
• Sells across eight therapeutic categories rather than specializing in weight management, and the GLP-1 products sit inside a broader peptide catalog
• Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven

RxPepsDirect is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• What microdosing GLP-1 costs
• Is compounded GLP-1 safe?
• Microdose & reconstitution calculator
• The true annual cost of a plan