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Low Dose GLP-1Providers

Provider review

Spry review

Prices with no billing period at all, and a four-week cycle disclosed only in the FAQ.

Four weeks is thirteen charges a year, so budgeting twelve of these figures falls about one charge short.

Reviewed by Lena OrtizMetabolic Health Editor

Price updated August 2026

How we’re funded. Some links here are affiliate links: start care through one and we may earn a commission, at no extra cost to you. Affiliate partners are listed first on our rankings — what we write about a provider is the same either way, and unflattering findings about one that pays us stay in. Full disclosure.

Price as published

Spry

$199 sema, $299 tirz — rebilled every four weeks, per its FAQ

Vs median
Not comparable — no per-month rate is published — the verified string carries no monthly figure
Market
$59–$1300/mo across 242 of 373
Structure
Standard plan, self-directed low dose
Dispensed
Pharmacy not publicly identified

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

In one paragraph

The verdict

A price with no period on it is the least comparable number in this whole category, and Spry publishes five of them. The cards give an amount and nothing else — not a month, not a supply length, not a vial count — so a reader arriving from a comparison naturally reads them as monthly rates, because that is what everything around them is. The company does say what the cycle is, and it says it clearly, but it says it inside a question about what happens after you order: you dose weekly for four weeks, and then you are rebilled and the next vial ships. Four weeks is not a month. Thirteen of those cycles fit in a year, so budgeting twelve of these figures leaves you short by roughly one charge, and the gap grows the longer you stay on treatment. That is why neither figure is treated as a monthly rate here. What the page does well is the clinical part. The screening criteria are named specifically — the thyroid and endocrine histories, the pancreatitis history, the pregnancy exclusion, the interacting medications — rather than gestured at, review is promised within a day by a named clinician type, and the company states a target rather than a testimonial. If you want a prescriber engaged with your case you will find more evidence of that here than the pricing presentation suggests.

Visit Spry

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

Who it suits, and who it does not

A good fit if

  • You want to know exactly what would disqualify you before you start an intake
  • You want a named clinician type reviewing your file within a day
  • You are buying vial by vial and do not need a calendar-month figure

Look elsewhere if

  • You are comparing monthly rates. Nothing on this site carries a billing period
  • You are budgeting a year. The real cycle is four weeks, so a year takes thirteen
  • You want a price tied to a milligram. None of the five figures is

What it actually costs

Price as published

No monthly rate is published. The product cards read "Starting at $199.00" for semaglutide and "Starting at $299.00" for tirzepatide with no period attached to either, and the billing cycle appears only in the company's own FAQ: "You take it weekly for 4 weeks, during which we re-bill you and ship your next vial" · four weeks is thirteen charges in a year rather than twelve, so neither figure is a monthly rate and treating it as one understates the year by about one charge · anti-aging products are priced the same way — BPC-157 from $249.00, NAD+ from $299.00 and sermorelin from $249.00, none carrying a period either · no dose sits behind any figure · a nurse practitioner is stated to review each file within twenty-four hours, with staff contact through the program and a stated minimum goal of ten percent weight reduction by four months · the FAQ names the contraindications it screens for specifically rather than in general terms

Vs median
Not comparable — no per-month rate is published — the verified string carries no monthly figure
Market
$59–$1300/mo is the full published spread in our ranking
Structure
Standard plan, self-directed low dose

No low-dose product of its own. Starting low means asking for a smaller amount inside a standard plan, at the standard plan's price.

152 of the 373 programs we track price a small dose this way. Not one figure on the site carries a billing period. The cards give an amount and nothing else — no month, no supply length, no vial count — so a reader arriving from a comparison reads them as monthly rates because everything around them is. The company does disclose the cycle, clearly, but only inside a question about what happens after ordering: dosing runs weekly for four weeks and then rebills. That is thirteen charges a year rather than twelve. ★ The clinical side is better than the pricing presentation suggests — the screening criteria are named specifically rather than gestured at, and review is promised within a day. No dose sits behind any figure and no low-dose product is offered.

Visit Spry

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

What is included

Consult
Included in the price
Dietitian
Not included
Labs
Not required
Pricing
Varies by dose, plan or tier
Price last updated
August 2026

What it does well

  • The screening criteria are named specifically rather than described in general terms.
  • A nurse practitioner is stated to review each file within twenty-four hours.
  • The billing cycle is disclosed in the company's own words, if only in the FAQ.

Pharmacy, labs and oversight

Spry does not publicly identify the pharmacy that fills its prescriptions. No bloodwork is required before you start. A clinician review is included in the price.

Transparency check

1 of 4 published openly

What Spry publishes about itself, read from its own pages when we verified them — not estimated, and not a score.

Pharmacy named and regulatedNo pharmacy is identified anywhere we could find on its own pages.
Not published
A price you can read before intakeThe figure appears only after an intake quiz, so it cannot be compared before signing up.
Not published
What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
Not published
No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
None on file

How the program works

A price with no period on it is the least comparable number in this whole category, and Spry publishes five of them. The cards give an amount and nothing else — not a month, not a supply length, not a vial count — so a reader arriving from a comparison naturally reads them as monthly rates, because that is what everything around them is. The company does say what the cycle is, and it says it clearly, but it says it inside a question about what happens after you order: you dose weekly for four weeks, and then you are rebilled and the next vial ships. Four weeks is not a month. Thirteen of those cycles fit in a year, so anyone budgeting twelve of these figures will be short by roughly one charge, and the gap grows the longer someone stays on treatment. That is the reason neither figure is treated as a monthly rate here. What the page does well is the clinical part. The screening criteria are named specifically — the thyroid and endocrine histories, the pancreatitis history, the pregnancy exclusion, the interacting medications — rather than gestured at, review is promised within a day by a named clinician type, and the company states a target rather than a testimonial. A reader who wants a prescriber engaged with their case will find more evidence of that here than the pricing presentation suggests.

The honest cons

No figure on the site carries a billing period, so none can be compared directly.
  • The real cycle is four weeks, which is thirteen charges a year rather than twelve.
  • No dose sits behind any figure.
Visit Spry

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

How it compares

Spry is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Where this sits

#246 of 373

Ordered with the companies that pay us first, and Spry is not one of them. A disclosed partition, not a score.

Compare all 373 providers →

Read this before you buy

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

Visit Spry

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

The closest alternative

RxSpan MD

From $194/mo

Vs median
$25/mo above the $169 median
Market
$59–$1300/mo across 242 of 373
Structure
Standard plan, self-directed low dose
Dispensed
Pharmacy not publicly identified

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

Read the RxSpan MD review →

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.