Provider review
Wholesome Clinic review
Prices three dose tiers per molecule, and charges a consultation before any of them.
Reviewed by Lena OrtizMetabolic Health Editor
Price updated August 2026
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$149/mo sema at 0.25–0.5 mg → $549/mo tirz at 12.5–15 mg
Visit Wholesome ClinicThe cost of titrating up is visible in advance, three tiers deep on each molecule. A consultation fee lands before the first prescription, and both injectables carry an added vitamin.
Price as published
Wholesome Clinic
$149/mo sema at 0.25–0.5 mg → $549/mo tirz at 12.5–15 mg
- Vs median
- $26/mo below the $175 median
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Quotes off the lowest dose
- Dispensed
- Pharmacy not publicly identified
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
In one paragraph
The verdict
This is one of the few places here where a reader can see what climbing the ladder will cost before they start it. Three priced tiers on semaglutide, three on tirzepatide, each keyed to a milligram range. On semaglutide the steps are gentle enough that a titration will not upend a budget. On tirzepatide they are not — the top tier costs well over three times the semaglutide starter, which is exactly the sort of thing worth knowing while choosing a molecule rather than eight months into one. There is also an oral dissolving tablet for patients who qualify, at the lowest figure on the page. Two things sit outside those headline numbers. A consultation is charged before any medication is dispensed, so the first month costs meaningfully more than the plan rate implies, and that is disclosed rather than hidden but easy to miss. And both injectables are compounded with something added — a vitamin in each case — so what is being priced is a combination preparation rather than the molecule alone. Common enough in this category, and not a problem in itself, but it makes a straight comparison against a plain compounded price inexact.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
Who it suits, and who it does not
A good fit if
- You want to see what each dose tier costs before you begin titrating.
- You may qualify for an oral dissolving tablet, priced at the lowest figure here.
- You would rather the consultation charge be stated up front than appear at checkout.
Look elsewhere if
- You are budgeting the first month. A consultation fee lands before any medication.
- You want the plain molecule. Both injectables are compounded with an added vitamin.
- You are heading toward a high tirzepatide dose. The top tier is more than triple the semaglutide starter.
What it actually costs
Price as published
$149/mo sema at 0.25–0.5 mg → $549/mo tirz at 12.5–15 mg
- Vs median
- $26/mo below the $175 median across the 299 of 548 programs here that publish a plain monthly rate
- Market
- $59–$1,300/mo is the full published spread on this site
- Structure
- Quotes off the lowest dose
States plainly that its advertised figures are based on the lowest dosage and that higher doses may cost more. On a general ranking that is a warning; for someone staying small it is the one model that bills accordingly.
49 of the 548 programs here price a small dose this way. Three priced dose levels per molecule, keyed to milligram ranges, with the price rising as the dose does. A consultation fee is charged before any medication, and both injectables are compounded with an added vitamin, so the figures price a combination preparation rather than the molecule alone.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
What is included
- Consult
- Confirm any separate fee
- Dietitian
- Not confirmed
- Labs
- Not required
- Pricing
- Check plan terms
What it does well
- Publishes three priced dose tiers for each molecule, so the cost of titrating up is visible in advance.
- Prices an oral dissolving tablet for qualifying patients at the lowest figure on the page.
- States the consultation charge up front rather than revealing it at checkout.
Pharmacy, labs and oversight
Wholesome Clinic does not publicly identify the pharmacy that fills its prescriptions. No bloodwork is required before you start. Confirm whether clinician visits cost extra.
Transparency check
2 of 4 published openly
What Wholesome Clinic publishes about itself, read from its own pages when we verified them — not estimated, and not a score.
- Pharmacy named and regulatedNo pharmacy is identified anywhere on its own pages.
- Not published
- A price you can read before intakeA monthly rate is published on its own pages — the figure in the price row above, read there and verified against it.
- Published
- What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
- Not published
- No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
- None on file
How the program works
Wholesome Clinic does the thing this site keeps asking for: it attaches milligrams to prices, three tiers deep on each molecule, so a reader can see exactly what climbing the ladder costs before they start it. On semaglutide the steps are gentle. On tirzepatide they are not — the top tier costs well over three times the semaglutide starter, which is a useful thing to know at the point of choosing a molecule rather than eight months into one. It also prices an oral dissolving tablet for patients who qualify, at the lowest figure on the page. Two things to factor in that the headline figures leave out. There is a consultation charge before any medication is dispensed, so the first month costs meaningfully more than the plan rate suggests. And both injectables are compounded with something else added — a vitamin in each case — so what is being priced is a combination preparation rather than the molecule alone. That is not unusual in this category and not necessarily a problem, but it makes a straight comparison against a plain compounded price inexact.
The honest cons
A consultation fee is charged before any medication, on top of the plan price.
- Both injectables are compounded with an added vitamin; the plain molecule is not priced.
- The tirzepatide ladder climbs steeply — its top tier is more than triple the semaglutide starter.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
How it compares
Wholesome Clinic is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.
Also consider
Two more programs to compare with Wholesome Clinic. Both are partners: we may earn a commission if you start care through these links.
Partner
SkinnyRx
$349/mo sema · $399/mo tirz
Same price at every dose
FDA warning letter · SkinnyRx · February 2026 · addressed to Lean Rx, Inc. dba SkinnyRx. Details in our review.
Partner
Oak
$250–$300/mo
No low-dose price published
Where this sits
#190 of 548
Ordered with the companies that pay us first, and Wholesome Clinic is not one of them. A disclosed partition, not a score.
Compare all 548 providers →Read this before you buy
Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.
- What microdosing GLP-1 costs
- Is compounded GLP-1 safe?
- Titration planner
- The true annual cost of a plan
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
Another program to compare
ShedRx (Shed)
$149–$199/mo microdose (2-month minimum)
- Vs median
- $26/mo below the $175 median
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Charges less for less
- Dispensed
- Pharmacy not publicly identified
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
Read the ShedRx (Shed) review →Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.