Wholesome Clinic review

This is one of the few places here where a reader can see what climbing the ladder will cost before they start it. Three priced tiers on semaglutide, three on tirzepatide, each keyed to a milligram range. On semaglutide the steps are gentle enough that a titration will not upend a budget. On tirzepatide they are not — the top tier costs well over three times the semaglutide starter, which is exactly the sort of thing worth knowing while choosing a molecule rather than eight months into one. There is also an oral dissolving tablet for patients who qualify, at the lowest figure on the page. Two things sit outside those headline numbers. A consultation is charged before any medication is dispensed, so the first month costs meaningfully more than the plan rate implies, and that is disclosed rather than hidden but easy to miss. And both injectables are compounded with something added — a vitamin in each case — so what is being priced is a combination preparation rather than the molecule alone. Common enough in this category, and not a problem in itself, but it makes a straight comparison against a plain compounded price inexact.

Vs median

$20/mo below the $169 median across the 242 of 373 programs we track that publish a plain monthly rate

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Quotes off the lowest dose

Consult

Billed separately

Dietitian

Not included

Labs

Not required

Pricing

Varies by dose, plan or tier

Price last updated

August 2026

Wholesome Clinic dispenses through a Not named facility. No bloodwork is required before you start. A clinician review is billed separately.

Wholesome Clinic does the thing this site keeps asking for: it attaches milligrams to prices, three tiers deep on each molecule, so a reader can see exactly what climbing the ladder costs before they start it. On semaglutide the steps are gentle. On tirzepatide they are not — the top tier costs well over three times the semaglutide starter, which is a useful thing to know at the point of choosing a molecule rather than eight months into one. It also prices an oral dissolving tablet for patients who qualify, at the lowest figure on the page. Two things to factor in that the headline figures leave out. There is a consultation charge before any medication is dispensed, so the first month costs meaningfully more than the plan rate suggests. And both injectables are compounded with something else added — a vitamin in each case — so what is being priced is a combination preparation rather than the molecule alone. That is not unusual in this category and not necessarily a problem, but it makes a straight comparison against a plain compounded price inexact.

A consultation fee is charged before any medication, on top of the plan price.

• Both injectables are compounded with an added vitamin; the plain molecule is not priced.
• The tirzepatide ladder climbs steeply — its top tier is more than triple the semaglutide starter.

Wholesome Clinic is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What microdosing GLP-1 costs
• Is compounded GLP-1 safe?
• Titration planner
• The true annual cost of a plan