Clume Health review

The plan structure is unusually clean for a low-dose reader: two named plans, a microdose one and a full-dose one, with the microdose forty dollars a month cheaper, and one price covering both molecules on either plan so there is no second table to reconcile. Both figures are readable before any intake, oral and injectable cost the same, and four dispensing pharmacies are named with street addresses and phone numbers. Then the front page undoes some of that goodwill. The two large prices printed there correspond to nothing on the plan cards, each carries an asterisk, and neither asterisk leads to a footnote anywhere on the page. On the cards themselves, the cheaper per-month figures are twelve-week and fifty-two-week term commitments sitting beside the month-to-month rate rather than alternatives to it. Nothing states a compounding class, nothing says which of the four named pharmacies fills a given order, and the terms reserve the right to move a prescription between them for pricing or operational reasons.

Vs median

$47/mo above the $172 median across the 254 of 393 programs we track that publish a plain monthly rate

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Charges less for less

Consult

Included in the price

Dietitian

Not included

Labs

Not required

Pricing

Varies by dose, plan or tier

Price last updated

September 2026

Clume Health dispenses through a RedRock · Health Warehouse · Precision Medicine · Triad Rx — designation not stated facility. No bloodwork is required before you start. A clinician review is included in the price.

Clume Health sells compounded semaglutide and compounded tirzepatide in oral and injectable form under two plan names, and the distinction between them is the one this site cares about: Signature is the full dose and Microdose/Maintain is the low one, priced forty dollars a month lower. One price covers both molecules on either plan, which makes the comparison unusually easy, and both figures are readable before any intake. The company names four dispensing pharmacies with street addresses and phone numbers, which is rare, and names OpenLoop as the practice behind the prescribing. The front page is where it goes wrong: the two large prices printed there correspond to nothing on the plan cards, each carries an asterisk, and neither asterisk leads to a footnote. Below them, the cheaper monthly figures on the cards are term commitments of twelve and fifty-two weeks presented alongside the month-to-month rate. Nothing states a compounding designation, nothing says which of the four pharmacies fills a given order, and the terms reserve the right to move a prescription between them for pricing or operational reasons.

THE TWO PRICES ON THE FRONT PAGE MATCH NOTHING THAT IS SOLD — $199 and $159 against real figures of $259, $219 and $216 — and neither asterisk beside them resolves to a footnote

• The cheaper per-month figures are term commitments: $200 needs twelve weeks and $186 needs fifty-two, both printed beside the month-to-month rate
• The cellular-optimization program has no month-to-month price at all
• Canceling requires 72 hours' notice, and a month already charged is not refunded
• The refund policy promises a 24/7 patient support line while no phone number appears anywhere and support is email only
• No compounding designation is stated, and the terms allow a prescription to be moved between the four pharmacies for pricing or operational reasons
• No milligram is published behind either plan
• Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven

Clume Health is one of 393 low-dose GLP-1 programs we track, and 254 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• What microdosing GLP-1 costs
• Low dose vs full dose
• The true annual cost of a plan
• What a flat price costs at a low dose