Defy Medical review

Defy Medical is a telemedicine practice whose catalog centers on hormone therapy, and it approaches weight loss the same way: labs first. Before any prescription you complete a comprehensive metabolic panel and a consultation with a provider, then repeat both at three months and every six months after that. It prescribes semaglutide, tirzepatide and liraglutide, and semaglutide also comes as a dissolving tablet or liquid drops. Existing patients can raise a GLP-1 at their next follow-up. That thoroughness suits someone whose weight may have a hormonal or thyroid cause. The cost is the blind spot. Defy does not take insurance, saying that keeps pricing predictable, yet no GLP-1 figure appears anywhere on the site, and the recurring labs and consultations add charges you cannot see in advance. There is no low-dose product, so a small dose would be a decision for your provider within ordinary care.

Vs median

Not comparable — no figure is published before intake

Market

$59–$1,300/mo is the full published spread on this site

Structure

Standard plan, self-directed low dose

Consult

Confirm any separate fee

Dietitian

Not confirmed

Labs

Required

Pricing

Check plan terms

Defy Medical does not publicly identify the pharmacy that fills its prescriptions. Bloodwork is required before you start. Confirm whether clinician visits cost extra.

Defy Medical is a telemedicine practice whose catalog centers on hormone therapy, and it also prescribes semaglutide, tirzepatide and liraglutide for weight loss. Semaglutide is also offered as a dissolving tablet and as liquid drops. Starting requires a comprehensive metabolic lab panel and a weight-management consultation with a Defy provider, then a follow-up consultation and new labs at three months, and every six months after that. Consultations are booked through its app once labs and paperwork are done, or by phone. Existing patients can ask to add a GLP-1 at a follow-up. Defy does not accept insurance or deal with insurers, which it says keeps pricing predictable, but no GLP-1 figure appears on the site. No low-dose product is offered.

No GLP-1 price appears anywhere on the site

• Labs and a consultation must be completed before you can be prescribed
• Follow-up labs every six months add a recurring cost that is not shown
• No insurance is accepted
• No low-dose or microdose product is offered
• Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven

Defy Medical is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• Oral semaglutide (Rybelsus)
• Low dose vs full dose
• The true annual cost of a plan
• Titration planner