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Low DoseGLP-1Providers

Provider review

Nucific review

A named microdose for both molecules, priced above the standard dose.

Reviewed by Lena OrtizMetabolic Health Editor

Price updated October 2026

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Microdose sema as low as $130 a month, tirz $150, plan length not stated

Visit Nucific

The microdose lines cost more than the standard ones, and no figure says which plan length it belongs to.

Price as published

Nucific

Microdose sema as low as $130 a month, tirz $150, plan length not stated

Vs median
Not comparable — no per-month rate is published — the verified string carries no monthly figure
Market
$59–$1,300/mo across 299 of 548
Structure
Prices the low dose on its own
Dispensed
Compounded by RedRock Pharmacy (St. George, Utah)

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

In one paragraph

The verdict

Nucific, the supplement brand, now runs a GLP-1 program through a telehealth medical practice, and it is one of the few that sells a microdose by name for both semaglutide and tirzepatide. That is the good news. The arithmetic is less good: its own as-low-as figure for each microdose is higher than its figure for the standard product, so the smaller dose is the more expensive line. None of the four figures says which plan length it belongs to, so treat all of them as floors rather than a monthly bill. The price is described as including labs and provider consultations, with no membership fee, and you get unlimited messaging with your provider. The compounding pharmacy is named in the terms, and brand-name Zepbound and Ozempic are available if you prefer them. Cancellation needs 72 hours' notice before billing, partial plan periods are not refunded, and payment runs through the medical practice's portal under its name. Its testimonials are paid.

Visit Nucific

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

Who it suits, and who it does not

A good fit if

  • You want a product sold as a microdose, on either molecule
  • You want labs and consultations included in the price
  • You want the pharmacy named

Look elsewhere if

  • You expect the microdose to cost less: here it costs more than the standard dose
  • You want a month-to-month price you can see before intake
  • You want refunds for an unused part of a plan

What it actually costs

Price as published

Microdose sema as low as $130 a month, tirz $150, plan length not stated

Vs median
Not comparable — no per-month rate is published — the verified string carries no monthly figure
Market
$59–$1,300/mo is the full published spread on this site
Structure
Prices the low dose on its own

Publishes a price for a microdose track, but no standard-dose price alongside it — so you can cost the low dose, you just cannot see what it saves you.

31 of the 548 programs here price a small dose this way. A named microdose product for each molecule with its own as-low-as figure, beside standard products whose figures are lower, so the smaller dose is the dearer line. No figure names a plan length, so none can be read as a monthly rate.

See Nucific's current price

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

What is included

Consult
Included in the price
Dietitian
Not confirmed
Labs
Required
Pricing
Check plan terms

What it does well

  • A microdose product is named and priced for both semaglutide and tirzepatide
  • Labs and provider consultations are included, with no membership fee
  • The dispensing pharmacy is named
  • Brand-name Zepbound and Ozempic are available alongside the compounded options
  • Unlimited messaging with your provider

Pharmacy, labs and oversight

Nucific names its pharmacy: RedRock Pharmacy (St. George, Utah). Bloodwork is required before you start. A clinician review is included in the price.

Transparency check

2 of 4 published openly

What Nucific publishes about itself, read from its own pages when we verified them — not estimated, and not a score.

Pharmacy named and regulatedNames its pharmacy: RedRock Pharmacy (St. George, Utah).
Published
A price you can read before intakeThe figure appears only after an intake quiz, so it cannot be compared before signing up.
Not published
What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
Not published
No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
None on file

How the program works

Nucific is a long-running supplement brand, operated by Pacific Health Supplements, LLC in Westlake Village, California, that now runs a GLP-1 telehealth program through OpenLoop Health's medical practice. It offers compounded semaglutide and tirzepatide, a microdose version of each, described as a smaller amount for a more gradual approach, and brand-name Zepbound and Ozempic. Labs and provider consultations are included, as is unlimited messaging with your provider. Compounded medication comes from RedRock Pharmacy in Utah, named in the terms. Payment, diagnosis and care happen in the medical practice's patient portal, and charges appear under the practice's name. It says it serves all 50 states and Washington, D.C., subject to change. It also sells NAD+, sermorelin and B12.

The honest cons

The microdose figures are higher than the standard ones: $130 against $117 for semaglutide, and $150 against $139 for tirzepatide
  • No figure names a plan length, so none can be read as a month-to-month rate
  • No refunds for partial plan periods, and cancellation needs 72 hours' notice before billing
  • No milligram is published for the microdose or the standard products
  • Its testimonials come from users who were paid for their time
  • Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven
Visit Nucific

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

How it compares

Nucific is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.

Also consider

Two more programs to compare with Nucific. Both are partners: we may earn a commission if you start care through these links.

Partner

yourEra

$179/mo microdose

Prices the low dose on its own

Partner

WellMedr

$59–$99/mo, but only on a 12-month plan

Same price at every dose

Where this sits

#461 of 548

Ordered with the companies that pay us first, and Nucific is not one of them. A disclosed partition, not a score.

Compare all 548 providers →

Read this before you buy

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

Start with Nucific

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

The closest alternative

CoreAge Rx

$149–$199/mo microdose ($99–$149 standard)

Vs median
$26/mo below the $175 median
Market
$59–$1,300/mo across 299 of 548
Structure
Prices the low dose on its own
Dispensed
Pharmacy not publicly identified

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

Read the CoreAge Rx review →

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.