Primary Clinic (Direct GLP) review

This site has now priced a great many providers and almost none of them will say what a dose costs. This one publishes the whole ladder. Semaglutide runs from eighty-five dollars a month at the smallest band up through four steps as the milligrams rise; tirzepatide does the same across its own four. Nobody has to guess, and nobody holding deliberately low is quietly funding the titration of somebody at the top of the range. That is the structure this site was built to find, and it is worth saying plainly because it is rare. The condition attached is equally plain, and to their credit it is stated rather than buried: those prices exist only for members, and membership is eighty-nine dollars a month. So the cheapest real figure is not eighty-five, it is one hundred and seventy-four, and any comparison against a flat-rate seller has to be made on that number rather than the headline. Whether that is good value depends entirely on whether you want what the membership includes — unlimited visits, direct provider messaging, routine labs and a long list of ordinary medications, all itemized. For someone who would otherwise pay for primary care anyway, this is likely the cheaper side of the trade. For someone who wants a vial and nothing else, it is eighty-nine dollars a month of things they did not come for.

Vs median

Not comparable — the published figure is not the whole bill — a membership, platform fee or separate medication charge sits on top of it

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Quotes off the lowest dose

Consult

Included in the price

Dietitian

Not included

Labs

Not required

Pricing

Varies by dose, plan or tier

Price last updated

August 2026

Primary Clinic (Direct GLP) dispenses through a Not named (described as licensed 503A pharmacies) facility. No bloodwork is required before you start. A clinician review is included in the price.

This is the structure this site has been looking for and has found almost nowhere else: a published price for each milligram band. Semaglutide starts at $85 a month for 0.25 to 0.75 mg and rises in four steps to $183 at 2.25 to 2.7 mg; tirzepatide runs the same way across four bands. Nobody has to guess what their dose costs, and someone holding deliberately low is billed for holding low rather than subsidizing the ladder above them. That is worth saying plainly because it is rare. The catch is equally plain, and to the clinic's credit it is stated rather than buried: none of those prices exist without the membership. Joining costs $89 a month, so the cheapest real monthly figure is $174 rather than $85, and any comparison against a flat-rate seller has to be made on that number. What the membership buys is itemized — unlimited visits, direct messaging, routine labs, and a long list of ordinary medications — so it is a bundle rather than a fee, and for someone who would otherwise pay separately for primary care it may be the cheaper side of the trade. For someone who only wants the drug, it is $89 a month of things they did not come for.

The medication prices are members-only, so the real low-dose cost is $174 a month rather than $85.

• Anyone who wants only the medication is paying $89 a month for primary care they did not come for.
• The compounding pharmacies are described as 503A but none is named.

Primary Clinic (Direct GLP) is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What microdosing GLP-1 costs
• Low dose vs full dose
• The true annual cost of a plan
• Titration planner