Provider review
Prime Doctor RX review
A real month-to-month price, billed every four weeks.
Reviewed by Lena OrtizMetabolic Health Editor
Price updated October 2026
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$249 per 4 weeks sema · $339 tirz · $279 oral sema, month to month
Visit Prime Doctor RXThe headline rates need a year paid up front; the rates you can actually pay monthly are printed beside them.
Price as published
Prime Doctor RX
$249 per 4 weeks sema · $339 tirz · $279 oral sema, month to month
- Vs median
- Not comparable — billed per four weeks, which is thirteen charges a year rather than twelve, so it is not a monthly rate
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Standard plan, self-directed low dose
- Dispensed
- Pharmacy not publicly identified
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
In one paragraph
The verdict
Prime Doctor RX is more open about its pricing than most: every product, compounded semaglutide and tirzepatide injections and an oral semaglutide tablet, shows a month-to-month price as well as prepaid rates for 12, 24 and 52 weeks. Two details shape what you actually pay. Billing is every four weeks, so a year is 13 charges, and the headline monthly figures belong to the 52-week plan paid up front, divided across 13 shipments. If you prepay and leave early, the terms let the company re-price the weeks you used at the shorter-term rate, so the saving is only real if you stay. There is no low-dose program and no milligram is published, so a small dose would be a request inside a standard plan at the standard price; the oral tablet is the easier route if you want one. Care runs through a national telehealth practice, with messaging and video or phone visits. The pharmacy is not named, and the states it serves for weight loss are not listed.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
Who it suits, and who it does not
A good fit if
- You want to see a month-to-month price before you start
- You want an oral semaglutide tablet
- You are sure enough to prepay for a year to get the lowest rate
Look elsewhere if
- You budget by the calendar month: billing is every four weeks
- You might stop early on a prepaid plan
- You want a product sold as a low dose
What it actually costs
Price as published
$249 per 4 weeks sema · $339 tirz · $279 oral sema, month to month
- Vs median
- Not comparable — billed per four weeks, which is thirteen charges a year rather than twelve, so it is not a monthly rate
- Market
- $59–$1,300/mo is the full published spread on this site
- Structure
- Standard plan, self-directed low dose
No low-dose product of its own. Starting low means asking for a smaller amount inside a standard plan, at the standard plan's price.
235 of the 548 programs here price a small dose this way. Every product carries a printed month-to-month rate and an oral semaglutide tablet is offered, but no low-dose product exists, so a small dose would be a request inside a standard plan. Billing is every four weeks, and the headline rates belong to a year paid up front.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
What is included
- Consult
- Included in the price
- Dietitian
- Not confirmed
- Labs
- Optional
- Pricing
- Check plan terms
What it does well
- A month-to-month price is printed for every product, alongside the prepaid rates
- Oral semaglutide is offered as a daily tablet
- Fees are shown before enrollment, with no separate membership
- Month-to-month plans can be canceled at any time with 72 hours' notice
- Video or phone visits as well as portal messaging
Pharmacy, labs and oversight
Prime Doctor RX does not publicly identify the pharmacy that fills its prescriptions. Bloodwork is offered but not required. A clinician review is included in the price.
Transparency check
2 of 4 published openly
What Prime Doctor RX publishes about itself, read from its own pages when we verified them — not estimated, and not a score.
- Pharmacy named and regulatedNo pharmacy is identified anywhere on its own pages.
- Not published
- A price you can read before intakeA monthly rate is published on its own pages — the figure in the price row above, read there and verified against it.
- Published
- What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
- Not published
- No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
- None on file
How the program works
Prime Doctor RX is a veteran- and firefighter-owned telehealth company in Houston, Texas, with clinical care from OpenLoop Healthcare Partners. For weight loss it sells compounded semaglutide by injection or as a daily tablet, and compounded tirzepatide by injection, each on a month-to-month plan or a prepaid plan of 12, 24 or 52 weeks; medication ships every four weeks. Care includes portal messaging and video or phone visits, with follow-up and refill review; labs are ordered when the clinical team thinks they are needed. The terms say medication may be filled by licensed pharmacies or other fulfillment providers, none named. The states served for weight loss are not listed. It also offers testosterone and enclomiphene. Nothing describes a microdose program.
The honest cons
Billing is every four weeks, so a year holds 13 charges
- The headline monthly figures need a 52-week plan paid up front
- Leaving a prepaid plan early can re-price the periods you used at the shorter-term rate
- The pharmacy is not named, and no milligram is published
- No low-dose program, and the states served for weight loss are not listed
- Compounded GLP-1s are not FDA-approved, and intentional microdosing is off-label and unproven
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
How it compares
Prime Doctor RX is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.
Also consider
Two more programs that price a small dose the way Prime Doctor RX does. Both are partners: we may earn a commission if you start care through these links.
Partner
Strut Health
$99/mo sema lozenge (auto-refill)
Standard plan, self-directed low dose
FDA warning letter · Strut Health · February 2026 · addressed to Strut Health, LLC dba Strut. Details in our review.
Partner
Willow
From $299/mo covering all four formats, none priced separately
Standard plan, self-directed low dose
Where this sits
#462 of 548
Ordered with the companies that pay us first, and Prime Doctor RX is not one of them. A disclosed partition, not a score.
Compare all 548 providers →Read this before you buy
Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.
- Oral semaglutide (Rybelsus)
- What microdosing GLP-1 costs
- Is compounded GLP-1 safe?
- The true annual cost of a plan
- Microdose & reconstitution calculator
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
The closest alternative
Peter MD
$149/mo GLP1+B12 · $249/mo tirz (quarterly)
- Vs median
- $26/mo below the $175 median
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Standard plan, self-directed low dose
- Dispensed
- Pharmacy not publicly identified
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
Read the Peter MD review →Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.