Provider review
SkyRx review
The semaglutide headline requires a year paid upfront.
Reviewed by Lena OrtizMetabolic Health Editor
Price updated October 2026
We may earn a commission at no extra cost to you. Affiliate partners are listed first on our rankings. How we’re funded.
Semaglutide $199 monthly equivalent; annual prepay
Visit SkyRxThe semaglutide starting equivalent requires twelve months prepaid and does not specify a microdose.
Price as published
SkyRx
Semaglutide $199 monthly equivalent; annual prepay
- Vs median
- Not comparable — no per-month rate is published — the verified string carries no monthly figure
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Standard plan, self-directed low dose
- Dispensed
- Compounded by Pharmxpress; Health Warehouse; BPI Labs; Precision
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
In one paragraph
The verdict
SkyRx’s headline is an annual commitment divided into months. That distinction is central to the buying decision, especially because ending and later restarting a subscription can add a charge. Its semaglutide injection and oral drops are different formulations even though the starting equivalent is the same. Review the full payment, cancellation terms and guarantee conditions before relying on the monthly headline; a microdose-specific saving is not published.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
Who it suits, and who it does not
A good fit if
- You are comfortable with a long prepaid treatment commitment
- You want to discuss injection and oral-drop formulations
Look elsewhere if
- You need monthly purchasing flexibility
- You want currently available tirzepatide from this service
What it actually costs
Price as published
Semaglutide $199 monthly equivalent; annual prepay
- Vs median
- Not comparable — no per-month rate is published — the verified string carries no monthly figure
- Market
- $59–$1,300/mo is the full published spread on this site
- Structure
- Standard plan, self-directed low dose
No low-dose product of its own. Starting low means asking for a smaller amount inside a standard plan, at the standard plan's price.
235 of the 548 programs here price a small dose this way. The semaglutide starting equivalent requires twelve months prepaid and does not specify a microdose.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
What is included
- Consult
- Included in the price
- Dietitian
- Not confirmed
- Labs
- Not stated
- Pricing
- Check plan terms
What it does well
- The injection and oral-drop options are priced publicly
- Named pharmacy partners appear in the terms
- Clinician review and ongoing support accompany the program
Pharmacy, labs and oversight
SkyRx names its pharmacy: Pharmxpress; Health Warehouse; BPI Labs; Precision. Laboratory requirements are not publicly stated; confirm them with the clinician. A clinician review is included in the price.
Transparency check
3 of 4 published openly
What SkyRx publishes about itself, read from its own pages when we verified them — not estimated, and not a score.
- Pharmacy named and regulatedNames its pharmacy: Pharmxpress; Health Warehouse; BPI Labs; Precision.
- Published
- A price you can read before intakeA monthly rate is published on its own pages — the figure in the price row above, read there and verified against it.
- Published
- What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
- Not published
- No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
- None on file
How the program works
SkyRx offers compounded semaglutide injections and oral drops, with clinician review, medication delivery and ongoing support. Both products carry the same starting monthly equivalent, but the footnote requires a twelve-month subscription paid in full upfront. The reviewed weight-loss page marks tirzepatide injections and drops as coming soon, so they are not treated here as currently available treatments. Pharmacy partners named in the terms include Pharmxpress, Health Warehouse, BPI Labs and Precision. Cancellation requires advance notice, and restarting after cancellation can trigger a reactivation charge. The advertised results guarantee also has substantial adherence and documentation conditions. No separately priced microdose product or weekly dose is attached to the annual offer. The public treatment information does not establish a mandatory laboratory schedule; confirm testing requirements with the clinician.
The honest cons
The starting monthly equivalent requires a full year paid upfront
- Tirzepatide is advertised as coming soon rather than available
- Reactivation and guarantee conditions require careful review
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
How it compares
SkyRx is one of 548 low-dose GLP-1 programs compared on this site, and 299 of them publish a monthly rate you can read before signing up. The full list puts every published price in one place, with the companies that pay us listed first — something we state there, on the page it applies to.
Also consider
Two more programs that price a small dose the way SkyRx does. Both are partners: we may earn a commission if you start care through these links.
Partner
Strut Health
$99/mo sema lozenge (auto-refill)
Standard plan, self-directed low dose
FDA warning letter · Strut Health · February 2026 · addressed to Strut Health, LLC dba Strut. Details in our review.
Partner
Peter MD
$149/mo GLP1+B12 · $249/mo tirz (quarterly)
Standard plan, self-directed low dose
Where this sits
#518 of 548
Ordered with the companies that pay us first, and SkyRx is not one of them. A disclosed partition, not a score.
Compare all 548 providers →Read this before you buy
Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.
Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.
The closest alternative
Willow
From $299/mo covering all four formats, none priced separately
- Vs median
- $124/mo above the $175 median
- Market
- $59–$1,300/mo across 299 of 548
- Structure
- Standard plan, self-directed low dose
- Dispensed
- Pharmacy not publicly identified
Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.
Read the Willow review →Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.