System Labs review

Start with what is unusually good about this one, because it is rare enough to say plainly: there is one product, one figure, and no ladder. No prepay rungs to decode, no membership fee sitting underneath, no per-visit charge, and the medication, the clinician review, the injection supplies and two-day temperature-controlled shipping are all stated as sitting inside the single monthly number. You can pause or cancel from the dashboard. The company puts that structure in its own FAQ rather than leaving you to reverse-engineer it, and it names three physicians on its medical board with their training rather than gesturing vaguely at licensed providers. Two caveats before you price it. The cheaper number on the page is a first-month introductory rate, and the page says so itself — it strikes the standing figure through and labels the discount as applying to the first month — so budgeting off it means budgeting for one month in twelve. And the single figure covers every dose: the buy box says so in as many words. That is reassuring if you expect to titrate all the way up, and it is the whole problem if you do not, because somebody deliberately holding at a starter amount is billed exactly what somebody at the top of the range is billed. There is no microdose protocol here, no low-dose tier, and no low-dose price published anywhere on the page — taking less means asking a prescriber for less inside the one standard plan and paying the standard price for the privilege. Three other things worth settling before you commit. It sells tirzepatide and nothing else, so there is no semaglutide option at any price. The dispensing pharmacy is never named, only described as a certified U.S. pharmacy. And no list of the states it serves is published anywhere — one of its named physicians is described as licensed in all fifty, which is a fact about that clinician rather than a statement about where the service is available.

Vs median

$10/mo above the $169 median across the 242 of 373 programs we track that publish a plain monthly rate

Market

$59–$1300/mo is the full published spread in our ranking

Structure

Same price at every dose

Consult

Included in the price

Dietitian

Not included

Labs

Not required

Pricing

Flat at every dose

Price last updated

August 2026

System Labs does not publicly identify the pharmacy that fills its prescriptions. No bloodwork is required before you start. A clinician review is included in the price.

System Labs (systemlabs.com), operated by System Laboratories, Inc., sells a single weight-loss product it calls Compounded GLP-1/GIP: a tirzepatide-based weekly subcutaneous injection, clinician-titrated, with injection supplies included. There is no semaglutide SKU — the molecule does not appear as a product on the lander this link resolves to — so a reader shopping semaglutide is at the wrong company. The commercial structure is unusually simple, and the company states it rather than leaving it to be inferred: a flat $179 a month, billed month to month, with free two-day temperature-controlled shipping, no membership fee and no per-visit fee, paused or canceled from the dashboard. There is no prepay ladder of any kind — no three-, six- or twelve-month rung — and one figure covers every dose, the buy box reading "Monthly Supply (All doses)". The first month is $99, which the lander's own price block shows by striking $179 through and labeling the cheaper figure "/first mo.". Getting in is a two-minute intake form, after which a licensed provider reviews it and reaches out by chat. On the only question this site asks, what is absent matters as much as what is priced: there is no microdose protocol, no low-dose tier and no low-dose figure published anywhere, so taking a deliberately small amount here means asking for less inside the one standard plan and paying the one standard price for it. Its medical board is named — Dr. Marc Gruner, Dr. Jonathan Hinds and Dr. Gregory Tennant — but the dispensing pharmacy is not, described only as a certified U.S. pharmacy, and no list of the states it serves is published anywhere.

One figure covers every dose — the buy box reads "Monthly Supply (All doses)" — so someone deliberately holding at a starter dose is billed exactly what someone at the top of the range is billed, and there is no cheaper low-dose product to move to instead

• No microdose protocol and no microdose-specific price is published anywhere on the lander. Nothing here is built around taking less: a small dose is a conversation with the prescriber inside the one standard plan, at the standard price
• $99 is a first-month introductory rate, not the rate. The standing figure is $179/mo, and the page labels the cheaper one "/first mo." itself, so anyone budgeting off $99 is budgeting for one month in twelve
• Tirzepatide only — there is no semaglutide product at all, so this is not a company to compare on a semaglutide price
• The dispensing pharmacy is never named, only "a certified U.S. pharmacy", so there is no compounding facility to look up and no 503A or 503B designation stated anywhere
• No list of the states it serves is published. One named physician is described as licensed in all 50 states, which is a fact about that clinician rather than a coverage claim about the service
• Its testimonials are first-name-and-age only and cannot be verified, and several of them praise its NAD+ and glutathione products rather than the GLP-1
• Compounded tirzepatide is not FDA-approved and is not a generic equivalent of Mounjaro or Zepbound — the lander carries its own bolded disclosure saying so — and intentional microdosing is off-label and unproven

System Labs is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

• What the evidence actually shows
• What microdosing GLP-1 costs
• Low dose vs full dose
• Microdose & reconstitution calculator
• What a flat price costs at a low dose