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Low Dose GLP-1Providers

Provider review

Open Water Rx review

The dual agonist is the cheaper of its two molecules — while a promotional code holds.

The regular price is published beside the promotional one, so you can see the ordering flip back.

Reviewed by Lena OrtizMetabolic Health Editor

Price updated August 2026

How we’re funded. Some links here are affiliate links: start care through one and we may earn a commission, at no extra cost to you. Affiliate partners are listed first on our rankings — what we write about a provider is the same either way, and unflattering findings about one that pays us stay in. Full disclosure.

Price as published

Open Water Rx

$249/mo sema · $219/mo tirz with a promo code

Vs median
$50/mo above the $169 median
Market
$59–$1300/mo across 242 of 373
Structure
Standard plan, self-directed low dose
Dispensed
Pharmacy not publicly identified

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

In one paragraph

The verdict

The pricing here does something almost nothing else does, and it does it with a coupon. Tirzepatide is a more expensive drug to compound than semaglutide, and virtually every seller prices it accordingly — usually thirty to eighty dollars a month higher. Open Water Rx quotes the dual agonist below the single one, which is genuinely the better deal if you want that molecule, and the whole of the reversal is a founder code. The stated regular price is published beside it, which is the honest way to run a promotion: you can see both scenarios and work out what happens when the code stops applying, and what happens is that the ordering returns to normal with a ninety-dollar gap the other way. Anyone choosing the dual agonist here on price should know they are choosing a promotional rate rather than a structural one. The rest of the presentation is better than average in ways that are easy to overlook. The states served are listed. The pharmacy relationship is stated. A certification claim is made with a verifiable seal rather than an unlinked badge. And the footer links the primary trial publications and the FDA's own shortage database instead of paraphrasing them, which lets you check the evidence rather than take a marketing summary of it. None of that answers the dose question, but it is a more checkable page than most.

Visit Open Water Rx

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

Who it suits, and who it does not

A good fit if

  • You want the dual agonist and are happy to buy while the promotional rate applies
  • You would rather a seller publish the post-promotion price than hide it
  • You want to read the underlying trials rather than a seller's summary of them

Look elsewhere if

  • You are budgeting long-term on the cheaper molecule. That ordering is coupon-dependent
  • You want semaglutide. Here it is the dearer of the two while the code holds
  • You want a figure attached to a milligram. Neither one is

What it actually costs

Price as published

Semaglutide $249/mo and tirzepatide $219/mo, the second conditional on the code FOUNDER against a stated regular price of $339/mo · ★★ that makes the dual agonist the cheaper of the two here, which reverses the ordering nearly every other seller uses — and the reversal exists only while the code applies; at the regular price tirzepatide is $90 dearer than semaglutide rather than $30 cheaper · both figures are published on the homepage before any intake and the site describes the practice as "radical transparency" with "clear pricing before checkout" · no dose sits behind either figure · the company states it is LegitScript-certified and links a seal for verification, states that pharmacy partners are licensed, and lists the states it serves · its own footer links the STEP 1 and SURMOUNT-1 trial publications and the FDA drug shortage database rather than summarizing them, which is unusual for a seller

Vs median
$50/mo above the $169 median across the 242 of 373 programs we track that publish a plain monthly rate
Market
$59–$1300/mo is the full published spread in our ranking
Structure
Standard plan, self-directed low dose

No low-dose product of its own. Starting low means asking for a smaller amount inside a standard plan, at the standard plan's price.

152 of the 373 programs we track price a small dose this way. ★★ The dual agonist is priced BELOW the single agonist, reversing the ordering nearly every other seller uses — and the whole reversal is a promotional code, with the regular price published beside it. Publishing both scenarios is the honest way to run a promotion: a reader can see that the ordering returns to normal, and widens, when the code stops applying. ★ The states served are listed, the pharmacy relationship stated, and the footer links the primary trial publications and the FDA shortage database rather than paraphrasing them, which lets a reader check the evidence instead of a summary of it. No dose sits behind either figure and no low-dose product is offered.

Visit Open Water Rx

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

What is included

Consult
Included in the price
Dietitian
Not included
Labs
Not required
Pricing
Varies by dose, plan or tier
Price last updated
August 2026

What it does well

  • Both molecules are priced on the homepage before any intake.
  • The regular price is published beside the promotional one, so the later cost is knowable.
  • The footer links primary trial publications and the FDA shortage database directly.

Pharmacy, labs and oversight

Open Water Rx does not publicly identify the pharmacy that fills its prescriptions. No bloodwork is required before you start. A clinician review is included in the price.

Transparency check

2 of 4 published openly

What Open Water Rx publishes about itself, read from its own pages when we verified them — not estimated, and not a score.

Pharmacy named and regulatedNo pharmacy is identified anywhere we could find on its own pages.
Not published
A price you can read before intakeA monthly rate is published on its own pages — the figure in the price row above, read there and verified against it.
Published
What a higher dose costsPriced by dose, plan or tier, and the higher rungs are not published — the advertised figure does not tell you what a larger dose costs.
Not published
No FDA warning letter on fileChecked against the FDA's own warning-letter database; nothing on file for this company.
None on file

How the program works

The pricing here does something almost nothing else on this page does, and it does it with a coupon. Tirzepatide is a more expensive drug to compound than semaglutide, and virtually every seller prices it accordingly — usually thirty to eighty dollars a month higher. Open Water Rx quotes the dual agonist below the single one, which is genuinely the better deal for anyone who wants that molecule, and the whole of the reversal is a founder code. The stated regular price is published beside it, which is the honest way to run a promotion: a reader can see both scenarios and work out what happens when the code stops applying, and what happens is that the ordering returns to normal with a ninety-dollar gap the other way. Anyone choosing tirzepatide here on price should know they are choosing a promotional rate rather than a structural one. The rest of the presentation is better than average in ways that are easy to overlook. The states served are listed. The pharmacy relationship is stated. A certification claim is made with a verifiable seal rather than an unlinked badge. And the footer links the primary trial publications and the FDA's own shortage database instead of paraphrasing them, which lets a reader check the evidence rather than take a marketing summary of it. None of that answers the dose question — no milligram appears anywhere — but it is a more checkable page than most.

The honest cons

The cheaper molecule is cheaper only while a promotional code applies.
  • At the stated regular price the ordering reverses and the gap widens.
  • No dose sits behind either figure.
Visit Open Water Rx

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

How it compares

Open Water Rx is one of 373 low-dose GLP-1 programs we track, and 242 of them publish a monthly rate you can read before signing up. The ranking lists every published price on one screen, ordered with the companies that pay us first — a mechanism we state there, on the page it applies to.

Where this sits

#243 of 373

Ordered with the companies that pay us first, and Open Water Rx is not one of them. A disclosed partition, not a score.

Compare all 373 providers →

Read this before you buy

Intentional GLP-1 microdosing is off-label and unproven — no randomized trial has established that a sub-label dose does anything, and any dose belongs with a clinician who knows your history. If you are going to have that conversation, have it with real numbers.

Visit Open Water Rx

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.

The closest alternative

RxSpan MD

From $194/mo

Vs median
$25/mo above the $169 median
Market
$59–$1300/mo across 242 of 373
Structure
Standard plan, self-directed low dose
Dispensed
Pharmacy not publicly identified

Advertising disclosure · we may earn a commission if you start care through some of these links, at no extra cost to you.

Read the RxSpan MD review →

Microdosing is off-label and unproven — decide with a clinician. Prices are as published by the provider when we last checked; confirm current terms before you buy.